Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4

Alejandro Villar-Prados; Sherry Y. Wu; Karem A. Court; Shaolin Ma; Christopher LaFargue; Mamur A. Chowdhury; Margaret I. Engelhardt; Cristina Ivan; Prahlad T. Ram; Ying Wang; Keith Baggerly; Cristian Rodriguez-Aguayo; Gabriel Lopez-Berestein; Shyh-Ming Yang; David J. Maloney; Makoto Yoshioka; Jeffrey W. Strovel; Jason Roszik; Anil K. Sood

doi:10.1158/1535-7163.MCT-18-0365

Cancer Biology and Translational Studies

Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4

Alejandro Villar-Prados, Sherry Y. Wu, Karem A. Court, Shaolin Ma, Christopher LaFargue, Mamur A. Chowdhury, Margaret I. Engelhardt, Cristina Ivan, Prahlad T. Ram, Ying Wang, Keith Baggerly, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Shyh-Ming Yang, David J. Maloney, Makoto Yoshioka, Jeffrey W. Strovel, Jason Roszik and Anil K. Sood

Alejandro Villar-Prados

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.

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Sherry Y. Wu

School of Biomedical Sciences, University of Queensland, Queensland, Australia.

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Karem A. Court

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Shaolin Ma

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Christopher LaFargue

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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ORCID record for Christopher LaFargue

Mamur A. Chowdhury

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Margaret I. Engelhardt

John P. and Kathrine G. McGovern Medical School, The University of Texas, Houston, Texas.

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Cristina Ivan

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Prahlad T. Ram

Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Ying Wang

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Keith Baggerly

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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Cristian Rodriguez-Aguayo

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Gabriel Lopez-Berestein

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Shyh-Ming Yang

National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.

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David J. Maloney

National Center for Advancing Translational Sciences, NIH, Rockville, Maryland.

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Makoto Yoshioka

ConverGene, Gaithersburg, Maryland.

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Jeffrey W. Strovel

ConverGene, Gaithersburg, Maryland.

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Jason Roszik

Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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For correspondence: asood@mdanderson.org jroszik@mdanderson.org

Anil K. Sood

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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For correspondence: asood@mdanderson.org jroszik@mdanderson.org

DOI: 10.1158/1535-7163.MCT-18-0365 Published February 2019

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February 2019
Volume 18, Issue 2

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Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4