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Molecular Cancer Therapeutics
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Small Molecule Therapeutics

CNDAC-Induced DNA Double-Strand Breaks Cause Aberrant Mitosis Prior to Cell Death

Xiaojun Liu, Yingjun Jiang, Kei-ichi Takata, Billie Nowak, Chaomei Liu, Richard D. Wood, Walter N. Hittelman and William Plunkett
Xiaojun Liu
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Yingjun Jiang
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Kei-ichi Takata
2Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Billie Nowak
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Chaomei Liu
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Richard D. Wood
2Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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Walter N. Hittelman
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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  • ORCID record for Walter N. Hittelman
William Plunkett
1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
3Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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  • ORCID record for William Plunkett
  • For correspondence: wplunket@mdanderson.org
DOI: 10.1158/1535-7163.MCT-18-1380 Published December 2019
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ARTICLE USAGE: September 2019 to January 2021

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Total1187209226

Cited By

Article Information

Volume 18, Issue 12, pp. 2283-2295

DOI 
https://doi.org/10.1158/1535-7163.MCT-18-1380
PubMed 
31501277

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received December 21, 2018
  • Revision received June 14, 2019
  • Accepted September 4, 2019
  • Published first September 9, 2019.

Article Versions

  • Previous version (September 9, 2019 - 06:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2019 American Association for Cancer Research.

Author Information

  1. Xiaojun Liu1,
  2. Yingjun Jiang1,
  3. Kei-ichi Takata2,
  4. Billie Nowak1,
  5. Chaomei Liu1,
  6. Richard D. Wood2,
  7. Walter N. Hittelman1, and
  8. William Plunkett1,3,*
  1. 1Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  2. 2Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  3. 3Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  1. ↵*Corresponding Author:
    William Plunkett, The University of Texas MD Anderson Cancer Center, 1901 East Road, Houston, TX 77054. Phone: 713-792-3335; E-mail: wplunket{at}mdanderson.org
  • Current address for K. Takata: Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.

  • Current address for X. Liu: School of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, TX.

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Molecular Cancer Therapeutics: 18 (12)
December 2019
Volume 18, Issue 12
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CNDAC-Induced DNA Double-Strand Breaks Cause Aberrant Mitosis Prior to Cell Death
Xiaojun Liu, Yingjun Jiang, Kei-ichi Takata, Billie Nowak, Chaomei Liu, Richard D. Wood, Walter N. Hittelman and William Plunkett
Mol Cancer Ther December 1 2019 (18) (12) 2283-2295; DOI: 10.1158/1535-7163.MCT-18-1380

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CNDAC-Induced DNA Double-Strand Breaks Cause Aberrant Mitosis Prior to Cell Death
Xiaojun Liu, Yingjun Jiang, Kei-ichi Takata, Billie Nowak, Chaomei Liu, Richard D. Wood, Walter N. Hittelman and William Plunkett
Mol Cancer Ther December 1 2019 (18) (12) 2283-2295; DOI: 10.1158/1535-7163.MCT-18-1380
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