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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics

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Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers

Correlation of Somatic Genomic Alterations Between Tissue Genomics and ctDNA Employing Next-Generation Sequencing: Analysis of Lung and Gastrointestinal Cancers

Omer M. Toor, Zaheer Ahmed, Waled Bahaj, Urooge Boda, Lee S. Cummings, Megan E. McNally, Kevin F. Kennedy, Timothy J. Pluard, Arif Hussain, Janakiraman Subramanian and Ashiq Masood
Omer M. Toor
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.Center for Precision Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
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Zaheer Ahmed
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.
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Waled Bahaj
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.
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Urooge Boda
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.
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Lee S. Cummings
Department of Surgery, University of Missouri Kansas City, Missouri.Division of Hepatobiliary Surgery, Saint Luke's Hospital, Kansas City, Missouri.
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Megan E. McNally
Division of Surgical Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
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Kevin F. Kennedy
Division of Cardiovascular Research, Saint Luke's Hospital, Kansas City, Missouri.
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Timothy J. Pluard
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.Center for Precision Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.Division of Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
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Arif Hussain
Division of Oncology, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.The Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
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Janakiraman Subramanian
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.Center for Precision Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.Division of Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
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Ashiq Masood
Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.Center for Precision Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.Division of Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
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  • For correspondence: amasood@saint-lukes.org
DOI: 10.1158/1535-7163.MCT-17-1015 Published May 2018
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Article Information

Volume 17, Issue 5, pp. 1123-1132

DOI 
https://doi.org/10.1158/1535-7163.MCT-17-1015
PubMed 
29500272

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received October 16, 2017
  • Revision received December 19, 2017
  • Accepted February 23, 2018
  • Published first March 2, 2018.

Article Versions

  • Previous version (March 2, 2018 - 06:54).
  • You are viewing the most recent version of this article.
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©2018 American Association for Cancer Research.

Author Information

  1. Omer M. Toor1,2,
  2. Zaheer Ahmed1,
  3. Waled Bahaj1,
  4. Urooge Boda1,
  5. Lee S. Cummings3,4,
  6. Megan E. McNally5,
  7. Kevin F. Kennedy7,
  8. Timothy J. Pluard1,2,6,
  9. Arif Hussain8,9,
  10. Janakiraman Subramanian1,2,6, and
  11. Ashiq Masood1,2,6,*
  1. 1Department of Medicine, University of Missouri Kansas City School of Medicine, Kansas City, Missouri.
  2. 2Center for Precision Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
  3. 3Department of Surgery, University of Missouri Kansas City, Missouri.
  4. 4Division of Hepatobiliary Surgery, Saint Luke's Hospital, Kansas City, Missouri.
  5. 5Division of Surgical Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
  6. 6Division of Oncology, Saint Luke's Cancer Institute, Kansas City, Missouri.
  7. 7Division of Cardiovascular Research, Saint Luke's Hospital, Kansas City, Missouri.
  8. 8Division of Oncology, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.
  9. 9The Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
  1. ↵*Corresponding Author:
    Ashiq Masood, University of Missouri School of Medicine, 4321 Washington St., Kansas City, MO 64111. Phone: 816-932-3300; Fax: 816-932-5793; E-mail: amasood{at}saint-lukes.org
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Molecular Cancer Therapeutics: 17 (5)
May 2018
Volume 17, Issue 5
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Correlation of Somatic Genomic Alterations Between Tissue Genomics and ctDNA Employing Next-Generation Sequencing: Analysis of Lung and Gastrointestinal Cancers
Omer M. Toor, Zaheer Ahmed, Waled Bahaj, Urooge Boda, Lee S. Cummings, Megan E. McNally, Kevin F. Kennedy, Timothy J. Pluard, Arif Hussain, Janakiraman Subramanian and Ashiq Masood
Mol Cancer Ther May 1 2018 (17) (5) 1123-1132; DOI: 10.1158/1535-7163.MCT-17-1015

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Correlation of Somatic Genomic Alterations Between Tissue Genomics and ctDNA Employing Next-Generation Sequencing: Analysis of Lung and Gastrointestinal Cancers
Omer M. Toor, Zaheer Ahmed, Waled Bahaj, Urooge Boda, Lee S. Cummings, Megan E. McNally, Kevin F. Kennedy, Timothy J. Pluard, Arif Hussain, Janakiraman Subramanian and Ashiq Masood
Mol Cancer Ther May 1 2018 (17) (5) 1123-1132; DOI: 10.1158/1535-7163.MCT-17-1015
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Molecular Cancer Therapeutics
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