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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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Therapeutic Agents: Small-Molecule Kinase Inhibitors

Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models

Sanjeeva P. Reddy, Dhanalakshmi Sivanandhan, Purushottam Dewang, Niranjan Rao, Roger A. Smith and Scott K. Thompson
Sanjeeva P. Reddy
1Asana Biosciences, Lawrenceville, NJ;
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Dhanalakshmi Sivanandhan
2Jubilant Biosys Ltd, #96 Industrial Suburb, II Stage Yeshwanthpur, India.
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Purushottam Dewang
2Jubilant Biosys Ltd, #96 Industrial Suburb, II Stage Yeshwanthpur, India.
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Niranjan Rao
1Asana Biosciences, Lawrenceville, NJ;
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Roger A. Smith
1Asana Biosciences, Lawrenceville, NJ;
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Scott K. Thompson
1Asana Biosciences, Lawrenceville, NJ;
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DOI: 10.1158/1535-7163.TARG-17-B150 Published January 2018
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Volume 17, Issue 1 Supplement, pp. B150

DOI 
https://doi.org/10.1158/1535-7163.TARG-17-B150

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514

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©2018 American Association for Cancer Research.

Author Information

  1. Sanjeeva P. Reddy1,
  2. Dhanalakshmi Sivanandhan2,
  3. Purushottam Dewang2,
  4. Niranjan Rao1,
  5. Roger A. Smith1, and
  6. Scott K. Thompson1
  1. 1Asana Biosciences, Lawrenceville, NJ;
  2. 2Jubilant Biosys Ltd, #96 Industrial Suburb, II Stage Yeshwanthpur, India.
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Molecular Cancer Therapeutics: 17 (1 Supplement)
January 2018
Volume 17, Issue 1 Supplement
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Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models
Sanjeeva P. Reddy, Dhanalakshmi Sivanandhan, Purushottam Dewang, Niranjan Rao, Roger A. Smith and Scott K. Thompson
Mol Cancer Ther January 1 2018 (17) (1 Supplement) B150; DOI: 10.1158/1535-7163.TARG-17-B150

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Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models
Sanjeeva P. Reddy, Dhanalakshmi Sivanandhan, Purushottam Dewang, Niranjan Rao, Roger A. Smith and Scott K. Thompson
Mol Cancer Ther January 1 2018 (17) (1 Supplement) B150; DOI: 10.1158/1535-7163.TARG-17-B150
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Therapeutic Agents: Small-Molecule Kinase Inhibitors

  • Abstract B161: Fragment-based discovery of a highly potent, orally bioavailable ERK1/2 inhibitor that modulates the phosphorylation and catalytic activity of ERK1/2
  • Abstract B155: Combining cell panel screening with analysis of gene expression levels reveals features of drug response and resistance
  • Abstract B170: Novel immunodeficient rat models offer a unique platform for drug efficacy studies in human tumor xenografts
Show more Therapeutic Agents: Small-Molecule Kinase Inhibitors

Therapeutic Agents: Small-Molecule Kinase Inhibitors: Poster Presentations - Proffered Abstracts

  • Abstract B161: Fragment-based discovery of a highly potent, orally bioavailable ERK1/2 inhibitor that modulates the phosphorylation and catalytic activity of ERK1/2
  • Abstract B155: Combining cell panel screening with analysis of gene expression levels reveals features of drug response and resistance
  • Abstract B170: Novel immunodeficient rat models offer a unique platform for drug efficacy studies in human tumor xenografts
Show more Therapeutic Agents: Small-Molecule Kinase Inhibitors: Poster Presentations - Proffered Abstracts
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Molecular Cancer Therapeutics
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