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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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About the Cover

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ABOUT THE COVER
Irradiation therapy for head and neck cancer frequently damages normal oral tissues including the salivary glands, resulting in loss of saliva producing acinar cells and reduced saliva production. Tyrosine kinase inhibitors (TKIs) provide robust radioprotection of salivary gland function, which is associated with salivary acinar cell regeneration. The cover shows aquaporin 5 stained acinar cells in the submandibular gland of mice treated with dasastinib in conjunction with irradiation. For more details, see article by Wie and colleagues on page 1989.

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Molecular Cancer Therapeutics: 16 (9)
September 2017
Volume 16, Issue 9
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Issue Highlights

  • Modeling Therapy Resistance in BRCA1/2-Mutant Cancers
  • Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma
  • Antitumor Synergism and Enhanced Survival with a Tumor Vasculature–Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide
  • A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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