Skip to main content
  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Large Molecule Therapeutics

Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates

Patrick J. Burke, Joseph Z. Hamilton, Scott C. Jeffrey, Joshua H. Hunter, Svetlana O. Doronina, Nicole M. Okeley, Jamie B. Miyamoto, Martha E. Anderson, Ivan J. Stone, Michelle L. Ulrich, Jessica K. Simmons, Erica E. McKinney, Peter D. Senter and Robert P. Lyon
Patrick J. Burke
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: pburke@seagen.com
Joseph Z. Hamilton
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Scott C. Jeffrey
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joshua H. Hunter
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Svetlana O. Doronina
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nicole M. Okeley
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jamie B. Miyamoto
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martha E. Anderson
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ivan J. Stone
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michelle L. Ulrich
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jessica K. Simmons
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erica E. McKinney
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter D. Senter
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert P. Lyon
Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI: 10.1158/1535-7163.MCT-16-0343 Published January 2017
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Online Impact

Statistics from Altmetric.com

ARTICLE USAGE

ARTICLE USAGE: November 2016 to February 2021

AbstractFull-text HTMLPDF
Total127161834304

Cited By

Article Information

Volume 16, Issue 1, pp. 116-123

DOI 
https://doi.org/10.1158/1535-7163.MCT-16-0343
PubMed 
28062707

Published By 
American Association for Cancer Research
Print ISSN 
1535-7163
Online ISSN 
1538-8514
History 
  • Received May 26, 2016
  • Revision received October 28, 2016
  • Accepted October 31, 2016
  • Published first November 9, 2016.

Article Versions

  • Previous version (November 9, 2016 - 10:11).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2016 American Association for Cancer Research.

Author Information

  1. Patrick J. Burke*,
  2. Joseph Z. Hamilton,
  3. Scott C. Jeffrey,
  4. Joshua H. Hunter,
  5. Svetlana O. Doronina,
  6. Nicole M. Okeley,
  7. Jamie B. Miyamoto,
  8. Martha E. Anderson,
  9. Ivan J. Stone,
  10. Michelle L. Ulrich,
  11. Jessica K. Simmons,
  12. Erica E. McKinney,
  13. Peter D. Senter, and
  14. Robert P. Lyon
  1. Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington.
  1. ↵*Corresponding Author:
    Patrick J. Burke, Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, WA 98021. Phone: 425-527-4766; Fax: 425-527-4109; E-mail: pburke{at}seagen.com
View Full Text
PreviousNext
Back to top
Molecular Cancer Therapeutics: 16 (1)
January 2017
Volume 16, Issue 1
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Editorial Board (PDF)

Sign up for alerts

View this article with LENS

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Molecular Cancer Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates
(Your Name) has forwarded a page to you from Molecular Cancer Therapeutics
(Your Name) thought you would be interested in this article in Molecular Cancer Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates
Patrick J. Burke, Joseph Z. Hamilton, Scott C. Jeffrey, Joshua H. Hunter, Svetlana O. Doronina, Nicole M. Okeley, Jamie B. Miyamoto, Martha E. Anderson, Ivan J. Stone, Michelle L. Ulrich, Jessica K. Simmons, Erica E. McKinney, Peter D. Senter and Robert P. Lyon
Mol Cancer Ther January 1 2017 (16) (1) 116-123; DOI: 10.1158/1535-7163.MCT-16-0343

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates
Patrick J. Burke, Joseph Z. Hamilton, Scott C. Jeffrey, Joshua H. Hunter, Svetlana O. Doronina, Nicole M. Okeley, Jamie B. Miyamoto, Martha E. Anderson, Ivan J. Stone, Michelle L. Ulrich, Jessica K. Simmons, Erica E. McKinney, Peter D. Senter and Robert P. Lyon
Mol Cancer Ther January 1 2017 (16) (1) 116-123; DOI: 10.1158/1535-7163.MCT-16-0343
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Disclosure of Potential Conflicts of Interest
    • Authors' Contributions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

More in this TOC Section

  • Improved Activity of CF10 in Preclinical Colorectal Cancer Models
  • Activity of ABBV-085 in Osteosarcoma
  • An Anti–CD22-seco-CBI-Dimer ADC for the Treatment of NHL
Show more Large Molecule Therapeutics
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About MCT

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

Advertisement