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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
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About the Cover

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Particle replication in nonwetting templates (PRINT) is a novel soft lithography process developed to fabricate nanotherapeutics. PRINT nanoparticles improve plasma exposure and increase tumor accumulation of the encapsulated therapeutic. Metronomic delivery of PLGA-PRINT-docetaxel nanoparticles combined with systemic EZH2 siRNA delivery using chitosan nanoparticles resulted in robust antitumor effects in ovarian cancer mouse models. For details, see the article by Gharpure and colleagues on page 1750.

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Molecular Cancer Therapeutics: 13 (7)
July 2014
Volume 13, Issue 7
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Issue Highlights

  • Metronomic Docetaxel in PRINT Nanoparticles and EZH2 Silencing Have Synergistic Antitumor Effect in Ovarian Cancer
  • Antibody-Based Delivery of IL2 and Cytotoxics Eradicates Tumors in Immunocompetent Mice
  • Combination of Anti-HER3 Antibody MM-121/SAR256212 and Cetuximab Inhibits Tumor Growth in Preclinical Models of Head and Neck Squamous Cell Carcinoma
  • Phosphoproteomics of MAPK Inhibition in BRAF-Mutated Cells and a Role for the Lethal Synergism of Dual BRAF and CK2 Inhibition
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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