Skip to main content
  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Table of Contents

Highlights

  • Highlights
    Highlights of This Issue
    Mol Cancer Ther March 1 2014 13 (3) 555-555;

Hypothesis/Commentary

  • Hypothesis/Commentary
    Advances in the Diagnosis and Treatment of Non–Small Cell Lung Cancer
    Rathi N. Pillai and Suresh S. Ramalingam
    Mol Cancer Ther March 1 2014 13 (3) 557-564; DOI:10.1158/1535-7163.MCT-13-0669

Small Molecule Therapeutics

  • Small Molecule Therapeutics
    A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo
    Fardokht Abulwerdi, Chenzhong Liao, Meilan Liu, Asfar S. Azmi, Amro Aboukameel, Ahmed S.A. Mady, Thippeswamy Gulappa, Tomasz Cierpicki, Scott Owens, Tao Zhang, Duxin Sun, Jeanne A. Stuckey, Ramzi M. Mohammad and Zaneta Nikolovska-Coleska
    Mol Cancer Ther March 1 2014 13 (3) 565-575; DOI:10.1158/1535-7163.MCT-12-0767

  • Small Molecule Therapeutics | AuthorChoice
    Combined MET Inhibition and Topoisomerase I Inhibition Block Cell Growth of Small Cell Lung Cancer
    Cleo E. Rolle, Rajani Kanteti, Mosmi Surati, Suvobroto Nandi, Immanuel Dhanasingh, Soheil Yala, Maria Tretiakova, Qudsia Arif, Todd Hembrough, Toni M. Brand, Deric L. Wheeler, Aliya N. Husain, Everett E. Vokes, Ajit Bharti and Ravi Salgia
    Mol Cancer Ther March 1 2014 13 (3) 576-584; DOI:10.1158/1535-7163.MCT-13-0109

  • Small Molecule Therapeutics
    The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas
    Michelle Agostini, Luciana Y. Almeida, Débora C. Bastos, Rose M. Ortega, Fernanda S. Moreira, Fabiana Seguin, Karina G. Zecchin, Helena F. Raposo, Helena C.F. Oliveira, Nivea D. Amoêdo, Tuula Salo, Ricardo D. Coletta and Edgard Graner
    Mol Cancer Ther March 1 2014 13 (3) 585-595; DOI:10.1158/1535-7163.MCT-12-1136

  • Small Molecule Therapeutics
    The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent
    Xiaona Liu, Rishi Raj Chhipa, Ichiro Nakano and Biplab Dasgupta
    Mol Cancer Ther March 1 2014 13 (3) 596-605; DOI:10.1158/1535-7163.MCT-13-0579

  • Small Molecule Therapeutics
    Disruption of STAT3 by Niclosamide Reverses Radioresistance of Human Lung Cancer
    Shuo You, Rui Li, Dongkyoo Park, Maohua Xie, Gabriel L. Sica, Ya Cao, Zhi-Qiang Xiao and Xingming Deng
    Mol Cancer Ther March 1 2014 13 (3) 606-616; DOI:10.1158/1535-7163.MCT-13-0608

  • Small Molecule Therapeutics
    TPCA-1 Is a Direct Dual Inhibitor of STAT3 and NF-κB and Regresses Mutant EGFR-Associated Human Non–Small Cell Lung Cancers
    Jing Nan, Yuping Du, Xing Chen, Qifeng Bai, Yuxin Wang, Xinxin Zhang, Ning Zhu, Jing Zhang, Jianwen Hou, Qin Wang and Jinbo Yang
    Mol Cancer Ther March 1 2014 13 (3) 617-629; DOI:10.1158/1535-7163.MCT-13-0464

  • Small Molecule Therapeutics
    Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α
    Tian-Yu Cai, Xiao-Wen Liu, Hong Zhu, Ji Cao, Jun Zhang, Ling Ding, Jian-Shu Lou, Qiao-Jun He and Bo Yang
    Mol Cancer Ther March 1 2014 13 (3) 630-642; DOI:10.1158/1535-7163.MCT-13-0490

Large Molecule Therapeutics

  • Large Molecule Therapeutics
    Immunoglobulin Fc Domain Fusion to TRAIL Significantly Prolongs Its Plasma Half-Life and Enhances Its Antitumor Activity
    Haizhen Wang, Jennifer S. Davis and Xiangwei Wu
    Mol Cancer Ther March 1 2014 13 (3) 643-650; DOI:10.1158/1535-7163.MCT-13-0645

  • Large Molecule Therapeutics
    Enhancement of the Tumor Penetration of Monoclonal Antibody by Fusion of a Neuropilin-Targeting Peptide Improves the Antitumor Efficacy
    Tae-Hwan Shin, Eun-Sil Sung, Ye-Jin Kim, Ki-Su Kim, Se-Ho Kim, Seok-Ki Kim, Young-Don Lee and Yong-Sung Kim
    Mol Cancer Ther March 1 2014 13 (3) 651-661; DOI:10.1158/1535-7163.MCT-13-0748

Cancer Biology and Signal Transduction

  • Cancer Biology and Signal Transduction
    Dinaciclib (SCH727965) Inhibits the Unfolded Protein Response through a CDK1- and 5-Dependent Mechanism
    Tri K. Nguyen and Steven Grant
    Mol Cancer Ther March 1 2014 13 (3) 662-674; DOI:10.1158/1535-7163.MCT-13-0714

  • Cancer Biology and Signal Transduction
    XPO1 (CRM1) Inhibition Represses STAT3 Activation to Drive a Survivin-Dependent Oncogenic Switch in Triple-Negative Breast Cancer
    Yan Cheng, Michael P. Holloway, Kevin Nguyen, Dilara McCauley, Yosef Landesman, Michael G. Kauffman, Sharon Shacham and Rachel A. Altura
    Mol Cancer Ther March 1 2014 13 (3) 675-686; DOI:10.1158/1535-7163.MCT-13-0416

  • Cancer Biology and Signal Transduction
    CBP-Mediated FOXO-1 Acetylation Inhibits Pancreatic Tumor Growth by Targeting SirT
    Kartick C. Pramanik, Neel M. Fofaria, Parul Gupta and Sanjay K. Srivastava
    Mol Cancer Ther March 1 2014 13 (3) 687-698; DOI:10.1158/1535-7163.MCT-13-0863

  • Cancer Biology and Signal Transduction | AuthorChoice
    Synuclein γ Compromises Spindle Assembly Checkpoint and Renders Resistance to Antimicrotubule Drugs
    Suyu Miao, Kejin Wu, Bo Zhang, Ziyi Weng, Mingjie Zhu, Yunshu Lu, Ramadas Krishna and Yuenian Eric Shi
    Mol Cancer Ther March 1 2014 13 (3) 699-713; DOI:10.1158/1535-7163.MCT-13-0671

  • Cancer Biology and Signal Transduction
    Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10–Mediated Paclitaxel Resistance: A Preclinical Study
    Rishil J. Kathawala, Kamlesh Sodani, Kang Chen, Atish Patel, Alaa H. Abuznait, Nagaraju Anreddy, Yue-Li Sun, Amal Kaddoumi, Charles R. Ashby Jr and Zhe-Sheng Chen
    Mol Cancer Ther March 1 2014 13 (3) 714-723; DOI:10.1158/1535-7163.MCT-13-0743

  • Cancer Biology and Signal Transduction | AuthorChoice
    Glioblastoma Cells Containing Mutations in the Cohesin Component STAG2 Are Sensitive to PARP Inhibition
    Melanie L. Bailey, Nigel J. O'Neil, Derek M. van Pel, David A. Solomon, Todd Waldman and Philip Hieter
    Mol Cancer Ther March 1 2014 13 (3) 724-732; DOI:10.1158/1535-7163.MCT-13-0749

  • Cancer Biology and Signal Transduction
    Mutant Ras Elevates Dependence on Serum Lipids and Creates a Synthetic Lethality for Rapamycin
    Darin Salloum, Suman Mukhopadhyay, Kaity Tung, Aleksandra Polonetskaya and David A. Foster
    Mol Cancer Ther March 1 2014 13 (3) 733-741; DOI:10.1158/1535-7163.MCT-13-0762

  • Cancer Biology and Signal Transduction
    microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites
    Steven M. Offer, Gabriel L. Butterfield, Calvin R. Jerde, Croix C. Fossum, Natalie J. Wegner and Robert B. Diasio
    Mol Cancer Ther March 1 2014 13 (3) 742-751; DOI:10.1158/1535-7163.MCT-13-0878

Tools and Technologies

  • Tools and Technologies | AuthorChoice
    Cancer-Associated CD43 Glycoforms as Target of Immunotherapy
    Franca Maria Tuccillo, Camillo Palmieri, Giuseppe Fiume, Annamaria de Laurentiis, Marco Schiavone, Cristina Falcone, Enrico Iaccino, Ricciarda Galandrini, Cristina Capuano, Angela Santoni, Francesco Paolo D'Armiento, Claudio Arra, Antonio Barbieri, Fabrizio Dal Piaz, David Venzon, Patrizia Bonelli, Franco Maria Buonaguro, Iris Scala, Massimo Mallardo, Ileana Quinto and Giuseppe Scala
    Mol Cancer Ther March 1 2014 13 (3) 752-762; DOI:10.1158/1535-7163.MCT-13-0651

Letters to the Editor

  • Letters to the Editor
    Sorafenib Inhibits ABCG2 and Overcomes Irinotecan Resistance—Letter
    Malcolm A. Smith
    Mol Cancer Ther March 1 2014 13 (3) 763-763; DOI:10.1158/1535-7163.MCT-13-0968

  • Letters to the Editor
    Sorafenib Inhibits ABCG2 and Overcomes Irinotecan Resistance—Response
    Céline Gongora
    Mol Cancer Ther March 1 2014 13 (3) 764-764; DOI:10.1158/1535-7163.MCT-13-1026

Back to top
PreviousNext
Molecular Cancer Therapeutics: 13 (3)
March 2014
Volume 13, Issue 3
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover

Sign up for alerts

Issue Highlights

  • TPCA-1 Is a Direct Dual Inhibitor of STAT3 and NF-κB and Regresses Mutant EGFR-Associated Human Non–Small Cell Lung Cancers
  • Enhancement of the Tumor Penetration of Monoclonal Antibody by Fusion of a Neuropilin-Targeting Peptide Improves the Antitumor Efficacy
  • A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo
  • Synuclein γ Compromises Spindle Assembly Checkpoint and Renders Resistance to Antimicrotubule Drugs
  • Cancer-Associated CD43 Glycoforms as Target of Immunotherapy

Jump to

  • Highlights
  • Hypothesis/Commentary
  • Small Molecule Therapeutics
  • Large Molecule Therapeutics
  • Cancer Biology and Signal Transduction
  • Tools and Technologies
  • Letters to the Editor
Advertisement
  • Most Cited
  • Most Read
Loading
  • CD137 Agonist mAb with Reduced Liver Toxicity
  • Truncated BRCA2 Contributes to PARPi Resistance
  • ERPAS to Predict Response to Endocrine Therapy
  • CDK8/19 Inhibitors Enhance NK-Cell–Mediated Cancer Therapy
  • Sialoglycan mAb for Cancer Immunotherapy
More...
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About MCT

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

Advertisement