Differential and Common DNA Repair Pathways for Topoisomerase I- and II-Targeted Drugs in a Genetic DT40 Repair Cell Screen Panel

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland

Departments of 1Radiation Genetics and 2Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University; 3Department of Urology, Graduate School of Medicine, Kyoto Prefectural University, Kyoto; 4Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan; and 5Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland