Table of Contents

Therapeutic Discovery

• Therapeutic Discovery

  GPR54 Is a Target for Suppression of Metastasis in Endometrial Cancer

  Hyun Sook Kang, Tsukasa Baba, Masaki Mandai, Noriomi Matsumura, Junzo Hamanishi, Budiman Kharma, Eiji Kondoh, Yumiko Yoshioka, Shinya Oishi, Nobutaka Fujii, Susan K. Murphy and Ikuo Konishi

  Mol Cancer Ther April 1 2011 10 (4) 580-590; DOI:10.1158/1535-7163.MCT-10-0763

  
  
• Therapeutic Discovery | Free Article

  Targeting the Replication Checkpoint Using SCH 900776, a Potent and Functionally Selective CHK1 Inhibitor Identified via High Content Screening

  Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Marc Labroli, Frances Shanahan, Nicole Davis, Lorena Taricani, Derek Wiswell, Wolfgang Seghezzi, Ervin Penaflor, Bhagyashree Bhagwat, Wei Wang, Danling Gu, Yunsheng Hsieh, Suining Lee, Ming Liu and David Parry

  Mol Cancer Ther April 1 2011 10 (4) 591-602; DOI:10.1158/1535-7163.MCT-10-0928

  
  
• Therapeutic Discovery

  Targeted Delivery of an Antibody–Mutant Human Endostatin Fusion Protein Results in Enhanced Antitumor Efficacy

  Seung-Uon Shin, Hyun-Mi Cho, Jaime Merchan, Jin Zhang, Krisztina Kovacs, Yawu Jing, Sundaram Ramakrishnan and Joseph D. Rosenblatt

  Mol Cancer Ther April 1 2011 10 (4) 603-614; DOI:10.1158/1535-7163.MCT-10-0804

  
  
• Therapeutic Discovery

  Novel Functions for mda-7/IL-24 and IL-24 delE5: Regulation of Differentiation of Acute Myeloid Leukemic Cells

  Bin-Xia Yang, Yong-Juan Duan, Cheng-Ya Dong, Fang Zhang, Wei-Feng Gao, Xue-Ying Cui, Yong-Min Lin and Xiao-Tong Ma

  Mol Cancer Ther April 1 2011 10 (4) 615-625; DOI:10.1158/1535-7163.MCT-10-0863

  
  
• Therapeutic Discovery

  Targeting Ovarian Tumor Cell Adhesion Mediated by Tissue Transglutaminase

  May Khanna, Bhadrani Chelladurai, Aruna Gavini, Liwei Li, Minghai Shao, David Courtney, John J. Turchi, Daniela Matei and Samy Meroueh

  Mol Cancer Ther April 1 2011 10 (4) 626-636; DOI:10.1158/1535-7163.MCT-10-0912

  
  
• Therapeutic Discovery

  Cancer-Targeted BikDD Gene Therapy Elicits Protective Antitumor Immunity against Lung Cancer

  Yuh-Pyng Sher, Shih-Jen Liu, Chun-Mien Chang, Shu-Pei Lien, Chien-Hua Chen, Zhenbo Han, Long-Yuan Li, Jin-Shing Chen, Cheng-Wen Wu and Mien-Chie Hung

  Mol Cancer Ther April 1 2011 10 (4) 637-647; DOI:10.1158/1535-7163.MCT-10-0827

  
  
• Therapeutic Discovery

  Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer

  Holly Symolon, Anatoliy Bushnev, Qiong Peng, Harsha Ramaraju, Suzanne G. Mays, Jeremy C. Allegood, Sarah T. Pruett, M. Cameron Sullards, Dirck L. Dillehay, Dennis C. Liotta and Alfred H. Merrill Jr.

  Mol Cancer Ther April 1 2011 10 (4) 648-657; DOI:10.1158/1535-7163.MCT-10-0754

  
  
• Therapeutic Discovery

  Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases

  Jie Yang, Donna McEachern, Wenyan Li, Mary A. Davis, Hua Li, Meredith A. Morgan, Longchuan Bai, Jonathan T. Sebolt, Haiying Sun, Theodore S. Lawrence, Shaomeng Wang and Yi Sun

  Mol Cancer Ther April 1 2011 10 (4) 658-669; DOI:10.1158/1535-7163.MCT-10-0643