Skip to main content
  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • First Disclosures
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Journals
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Cancer Therapeutics

Molecular Cancer Therapeutics

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Focus on Radiation Oncology
      • Novel Combinations
      • Reviews
      • Editors' Picks
      • "Best of" Collection
  • First Disclosures
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

The AACR remains fully committed to supporting publishing operations throughout this challenging time, while still remaining flexible and supportive of the author, reviewer, and editor communities that we serve. If you have any questions or concerns, please reach out to a member of the AACR publishing staff.
Please visit the COVID-19 & Cancer Resource Center where COVID-related content is freely available.

 

Follow @MCT_AACR on Twitter!

  • Current cover for Molecular Cancer Therapeutics
    April 2021
    Read the April issue!
  • First Disclosure
    First Disclosure: F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd
    Joel Morris, et al.
  • ERK Inhibitor LY3214996-Based Treatment Strategies
    ERK Inhibitor LY3214996-Based Treatment Strategies for RAS-Driven Lung Cancer
    Jens Köhler, et al.
  • Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody
    Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
    Amy A. Lo, et al.
  • 1
  • 2
  • 3
  • 4

From the Current Issue

  • Review
    Role of Polo-Like Kinase 4 (PLK4) in Epithelial Cancers and Recent Progress in its Small Molecule Targeting for Cancer Management
    Debra R. Garvey, Gagan Chhabra, Mary A. Ndiaye and Nihal Ahmad
    Mol Cancer Ther April 1 2021 20 (4) 632-640; DOI:10.1158/1535-7163.MCT-20-0741

  • Small Molecule Therapeutics
    ERK Inhibitor LY3214996-Based Treatment Strategies for RAS-Driven Lung Cancer
    Jens Köhler, Yutong Zhao, Jiaqi Li, Prafulla C. Gokhale, Hong L. Tiv, Aine R. Knott, Margaret K. Wilkens, Kara M. Soroko, Mika Lin, Chiara Ambrogio, Monica Musteanu, Atsuko Ogino, Jihyun Choi, Magda Bahcall, Arrien A. Bertram, Emily S. Chambers, Cloud P. Paweletz, Shripad V. Bhagwat, Jason R. Manro, Ramon V. Tiu and Pasi A. Jänne
    Mol Cancer Ther April 1 2021 20 (4) 641-654; DOI:10.1158/1535-7163.MCT-20-0531

  • Large Molecule Therapeutics
    Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
    Amy A. Lo, Jennifer Johnston, Ji Li, Danielle Mandikian, Maria Hristopoulos, Robyn Clark, Dorothee Nickles, Wei-Ching Liang, Kathy Hötzel, Debra Dunlap, Thinh Pham, Hao Cai, Meric Ovacik, Daniel Bravo-Perez, Elaine Mai, Dionysos Slaga, Diego Ellerman, James Ziai, Klara Totpal, Genee Lee, C. Andrew Boswell, Jian Payandeh, Yan Wu and Teemu T. Junttila
    Mol Cancer Ther April 1 2021 20 (4) 716-725; DOI:10.1158/1535-7163.MCT-20-0490

  • Cancer Biology and Translational Studies
    Lipidome-based Targeting of STAT3-driven Breast Cancer Cells Using Poly-l-glutamic Acid–coated Layer-by-Layer Nanoparticles
    Isidora Tošić, Lisa N. Heppler, Susana P. Egusquiaguirre, Natalie Boehnke, Santiago Correa, Daniel F. Costa, Elizabeth A. Grossman Moore, Sharmistha Pal, Douglas S. Richardson, Alexander R. Ivanov, Daphne A. Haas-Kogan, Daniel K. Nomura, Paula T. Hammond and David A. Frank
    Mol Cancer Ther April 1 2021 20 (4) 726-738; DOI:10.1158/1535-7163.MCT-20-0505

  • Models and Technologies | AuthorChoice
    Isoform- and Phosphorylation-specific Multiplexed Quantitative Pharmacodynamics of Drugs Targeting PI3K and MAPK Signaling in Xenograft Models and Clinical Biopsies
    William G. Herrick, Casey L. Kilpatrick, Melinda G. Hollingshead, Dominic Esposito, Geraldine O'Sullivan Coyne, Andrea M. Gross, Barry C. Johnson, Alice P. Chen, Brigitte C. Widemann, James H. Doroshow, Ralph E. Parchment and Apurva K. Srivastava
    Mol Cancer Ther April 1 2021 20 (4) 749-760; DOI:10.1158/1535-7163.MCT-20-0566

See the Table of Contents


Recent Reviews

  • Review | AuthorChoice
    Salting the Soil: Targeting the Microenvironment of Brain Metastases
    Ethan S. Srinivasan, Aaron C. Tan, Carey K. Anders, Ann Marie Pendergast, Dorothy A. Sipkins, David M. Ashley, Peter E. Fecci and Mustafa Khasraw
    Mol Cancer Ther March 1 2021 20 (3) 455-466; DOI:10.1158/1535-7163.MCT-20-0579

  • Reviews
    Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides
    Jamie V. Shiah, Jennifer R. Grandis and Daniel E. Johnson
    Mol Cancer Ther February 1 2021 20 (2) 219-228; DOI:10.1158/1535-7163.MCT-20-0599

  • Reviews
    Therapeutic Vulnerabilities of Transcription Factors in AML
    Irum Khan, Elizabeth E. Eklund and Andrei L. Gartel
    Mol Cancer Ther February 1 2021 20 (2) 229-237; DOI:10.1158/1535-7163.MCT-20-0115

OnlineFirst Articles

  • Computer-Aided Discovery of a Bcl3 Inhibitor
    Jitka Soukupová, et al.
  • Preclinical Assessment of EGFRvIII-specific BiTE Molecule
    Alexander Sternjak, et al.
  • IL4R in Rhabdomyosarcoma
    Megan M. Cleary, et al.
  • IMD-0354, a Glutamine Carrier Protein Inhibitor in Melanoma
    Yongmei Feng, et al.
Load more

Trending - Altmetric

No Altmetric data available.
Advertisement

 

Back to top
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About MCT

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

Advertisement