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Molecular Cancer Therapeutics

Molecular Cancer Therapeutics

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The AACR remains fully committed to supporting publishing operations throughout this challenging time, while still remaining flexible and supportive of the author, reviewer, and editor communities that we serve. If you have any questions or concerns, please reach out to a member of the AACR publishing staff.
Please visit the COVID-19 & Cancer Resource Center where COVID-related content is freely available.

 

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  • Current cover for Molecular Cancer Therapeutics
    March 2021
    Read the March issue!
  • Preclinical Characterization of Linrodostat Mesylate
    Preclinical Characterization of Linrodostat Mesylate, a Novel, Potent, and Selective Oral Indoleamine 2,3-Dioxygenase 1 Inhibitor
    Aaron Balog, et al.
  • Exosome Surface Display of IL12
    Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12
    Nuruddeen D. Lewis, et al.
  • Targeting Radiation-Resistant Prostate Cancer Stem Cells
    Targeting Radiation-Resistant Prostate Cancer Stem Cells by B7-H3 CAR T Cells
    Yida Zhang, et al.
  • 1
  • 2
  • 3
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From the Current Issue

  • Review | AuthorChoice
    Salting the Soil: Targeting the Microenvironment of Brain Metastases
    Ethan S. Srinivasan, Aaron C. Tan, Carey K. Anders, Ann Marie Pendergast, Dorothy A. Sipkins, David M. Ashley, Peter E. Fecci and Mustafa Khasraw
    Mol Cancer Ther March 1 2021 20 (3) 455-466; DOI:10.1158/1535-7163.MCT-20-0579

  • Small Molecule Therapeutics
    Preclinical Characterization of Linrodostat Mesylate, a Novel, Potent, and Selective Oral Indoleamine 2,3-Dioxygenase 1 Inhibitor
    Aaron Balog, Tai-an Lin, Derrick Maley, Johnni Gullo-Brown, Enzo Hamza Kandoussi, Jianing Zeng and John T. Hunt
    Mol Cancer Ther March 1 2021 20 (3) 467-476; DOI:10.1158/1535-7163.MCT-20-0251

  • Large Molecule Therapeutics | AuthorChoice
    Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12
    Nuruddeen D. Lewis, Chang Ling Sia, Katherine Kirwin, Sonya Haupt, Gauri Mahimkar, Tong Zi, Ke Xu, Kevin Dooley, Su Chul Jang, Bryan Choi, Adam Boutin, Andrew Grube, Christine McCoy, Jorge Sanchez-Salazar, Michael Doherty, Leonid Gaidukov, Scott Estes, Kyriakos D. Economides, Douglas E. Williams and Sriram Sathyanarayanan
    Mol Cancer Ther March 1 2021 20 (3) 523-534; DOI:10.1158/1535-7163.MCT-20-0484

  • Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers
    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
    Marika K.A. Koivu, Deepankar Chakroborty, Mahlet Z. Tamirat, Mark S. Johnson, Kari J. Kurppa and Klaus Elenius
    Mol Cancer Ther March 1 2021 20 (3) 564-576; DOI:10.1158/1535-7163.MCT-20-0590

  • Cancer Biology and Translational Studies | AuthorChoice
    Targeting Radiation-Resistant Prostate Cancer Stem Cells by B7-H3 CAR T Cells
    Yida Zhang, Lile He, Ananthan Sadagopan, Tao Ma, Gianpietro Dotti, Yufeng Wang, Hui Zheng, Xin Gao, Dian Wang, Albert B. DeLeo, Song Fan, Ruochuan Sun, Ling Yu, Liyuan Zhang, Gongxian Wang, Soldano Ferrone and Xinhui Wang
    Mol Cancer Ther March 1 2021 20 (3) 577-588; DOI:10.1158/1535-7163.MCT-20-0446

See the Table of Contents


Recent Reviews

  • Reviews
    Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides
    Jamie V. Shiah, Jennifer R. Grandis and Daniel E. Johnson
    Mol Cancer Ther February 1 2021 20 (2) 219-228; DOI:10.1158/1535-7163.MCT-20-0599

  • Reviews
    Therapeutic Vulnerabilities of Transcription Factors in AML
    Irum Khan, Elizabeth E. Eklund and Andrei L. Gartel
    Mol Cancer Ther February 1 2021 20 (2) 229-237; DOI:10.1158/1535-7163.MCT-20-0115

  • Review
    Targeting PIM Kinases to Overcome Therapeutic Resistance in Cancer
    Rachel K. Toth and Noel A. Warfel
    Mol Cancer Ther January 1 2021 20 (1) 3-10; DOI:10.1158/1535-7163.MCT-20-0535

OnlineFirst Articles

  • Targeting BET and PI3K in Ovarian Clear Cell Carcinoma
    Shogo Shigeta, et al.
  • V-ATPase Inhibition and AR Activity in Prostate Cancer
    Bradleigh Whitton, et al.
  • Anti-invasive and antimetastatic effects of JZL184
    Jan Lukas PrĂ¼ser, et al.
  • Anti-CD19 CAR with favorable efficacy to toxicity balance
    Alka Dwivedi, et al.
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    Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress
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Copyright © 2021 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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