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Read the August 2019 issue!
Cover image from "Sentinel Lymph Node–Targeted Therapy by Oncolytic Sendai Virus Suppresses Micrometastasis of Head and Neck Squamous Cell Carcinoma in an Orthotopic Nude Mouse Model" by Tanaka and colleagues.
EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer
Suryavathi Viswanadhapalli, et al.
Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in KRAS-Mutant Cancers
Adam Stewart, et al.
Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing
Sunetra Das, et al.

From the Current Issue

Small Molecule Therapeutics

EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer

Suryavathi Viswanadhapalli, Yiliao Luo, Gangadhara R. Sareddy, Bindu Santhamma, Mei Zhou, Mengxing Li, Shihong Ma, Rajni Sonavane, Uday P. Pratap, Kristin A. Altwegg, Xiaonan Li, Annabel Chang, Alejandra Chávez-Riveros, Kalarickal V. Dileep, Kam Y.J. Zhang, Xinlei Pan, Ramachandran Murali, Marek Bajda, Ganesh V. Raj, Andrew J. Brenner, Vijaya Manthati, Manjeet K. Rao, Rajeshwar R. Tekmal, Hareesh B. Nair, Klaus J. Nickisch and Ratna K. Vadlamudi

Mol Cancer Ther August 1 2019 18 (8) 1341-1354; DOI:10.1158/1535-7163.MCT-18-1258
Large Molecule Therapeutics

A Short SOX9 Peptide Mimics SOX9 Tumor Suppressor Activity and Is Sufficient to Inhibit Colon Cancer Cell Growth

Philippe Blache, Lucile Canterel-Thouennon, Muriel Busson, Pascal Verdié, Gilles Subra, Marc Ychou and Corinne Prévostel

Mol Cancer Ther August 1 2019 18 (8) 1386-1395; DOI:10.1158/1535-7163.MCT-18-1149
Cancer Biology and Translational Studies | AuthorChoice

Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in KRAS-Mutant Cancers

Adam Stewart, Elizabeth A. Coker, Sebastian Pölsterl, Alexandros Georgiou, Anna R. Minchom, Suzanne Carreira, David Cunningham, Mary ER. O'Brien, Florence I. Raynaud, Johann S. de Bono, Bissan Al-Lazikani and Udai Banerji

Mol Cancer Ther August 1 2019 18 (8) 1396-1404; DOI:10.1158/1535-7163.MCT-18-0727
Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers

Prognostic and Biologic Relevance of Clinically Applicable Long Noncoding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia

Dimitrios Papaioannou, Deedra Nicolet, Hatice G. Ozer, Krzysztof Mrózek, Stefano Volinia, Paolo Fadda, Andrew J. Carroll, Jessica Kohlschmidt, Jonathan E. Kolitz, Eunice S. Wang, Richard M. Stone, John C. Byrd, Ramiro Garzon and Clara D. Bloomfield

Mol Cancer Ther August 1 2019 18 (8) 1451-1459; DOI:10.1158/1535-7163.MCT-18-1125
Models and Technologies

Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing

Sunetra Das, Rupa Idate, Kathryn E. Cronise, Daniel L. Gustafson and Dawn L. Duval

Mol Cancer Ther August 1 2019 18 (8) 1460-1471; DOI:10.1158/1535-7163.MCT-18-1346

See the Table of Contents

Recent Reviews

Review

What CAR Will Win the CD19 Race?

Alfonso Quintás-Cardama

Mol Cancer Ther March 1 2019 18 (3) 498-506; DOI:10.1158/1535-7163.MCT-18-1070
Reviews

Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer

Lin Zhang, Dan Peng, Anil K. Sood, Chi V. Dang and Xiaomin Zhong

Mol Cancer Ther September 1 2018 17 (9) 1816-1823; DOI:10.1158/1535-7163.MCT-18-0124
Reviews

We're Not “DON” Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine

Kathryn M. Lemberg, James J. Vornov, Rana Rais and Barbara S. Slusher

Mol Cancer Ther September 1 2018 17 (9) 1824-1832; DOI:10.1158/1535-7163.MCT-17-1148
Reviews

Targeted Therapy–based Combination Treatment in Rhabdomyosarcoma

Anke E.M. van Erp, Yvonne M.H. Versleijen-Jonkers, Winette T.A. van der Graaf and Emmy D.G. Fleuren

Mol Cancer Ther July 1 2018 17 (7) 1365-1380; DOI:10.1158/1535-7163.MCT-17-1131

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