Table 1.

Physical characteristics of PM-based formulations

FormulationMean diameter (nm ± SD)P.I. ± SDSurvivin siRNA incorporation efficiency (% ± SD)PXL incorporation efficiency (% ± SD)
Survivin siRNA/PXL PM25.0 ± 3.60.190 ± 0.0751.0 ± 2.589.9 ± 3.5
Survivin siRNA PM23.0 ± 2.10.182 ± 0.1050.6 ± 1.5
Scrambled siRNA/PXL PM22.9 ± 1.50.195 ± 0.0552.2 ± 3.090.1 ± 2.4