Table 3.

In vivo biomarker modulation in s.c. U87MG aGB human tumor xenografts in mice treated with 17-AAG and NVP-AUY for 3 days, as described in Fig. 6

T/C (%)17-AAGNVP-AUY922
24 h48 h24 h48 h
HSP72344246360173
P-ERK878911243
ERK1288913296
P-AKT787010236*
AKT52*689055*
HIF1α144907064
P-MET33*3628*11
MET444539*20
VEGF5533*19885