Table 1.

Summary of leukemia subtype, MGMT activity, and MSI status in leukemia cell lines

Cell lineLeukemia subtypeMGMT activity (fmol/mg protein)MSIGroup*
U937AMLAbsentStableS0
HELAMLAbsentStableS0
THP1AMLLow (370 ± 11)StableS1
JM1Pre-B ALLLow (450 ± 17)StableS1
RajiB ALLAverage (380 ± 89)StableS1
HL-60AMLAverage (750 ± 94)StableS2
DaudiB ALLAverage (902 ± 17)StableS2
KG1AMLHigh (1,170 ± 34)StableS3
HSB2T-ALLLow (320 ± 20)UnstableU1
Molt4T-ALLAverage (560 ± 37)UnstableU2
JurkatT-ALLHigh (1,290 ± 36)UnstableU3
RehPre-B ALLHigh (1,300 ± 14)UnstableU3
  • *Group assignment based on MGMT activity (0 = none, 1 = low, 2 = medium, 3 = high) and MSI status (S = stable, U = unstable).