Table 1.

Top 20 upregulated and top 20 downregulated genes in T98G cells relative to U87MG cells

Gene symbolFold difference*Gene nameFunctionLocalizationProbeSet IDP
IGFBP58,64Insulin-like growth factor binding protein 5SignalingSecreted211959_at6,20E-09
CDH67,89Cadherin 6, type 2, K-cadherin (fetal kidney)AdhesionPlasma membrane205532_s_at1,53E.-08
THBS17,88Thrombospondin 1Adhesion/signalingSecreted/ECM201109_s_at2.30E-08
CDH117,38Cadherin 11, type 2, OR-cadherin (osteoblast)AdhesionPlasma membrane207173_x_at7,51E-08
TNFRSF11B6,83Tumor necrosis factor receptor superfamily, member 11bSignalingSecreted204933_s_at2,3OE-08
GSTM36,81GST M3 (brain)RedoxIntracellular202554_s_at2,30E-08
CXCL126,70Chemokine(C-X-Cmotif) ligand 12 (stromal cell–derived factor 1)SignalingSecreted209687_at5,85E-08
GPX36,64Glutathione peroxidase 3 (plasma)RedoxSecreted201348_at9.93E-09
MYH106,51Myosin, heavy chain 10, nonmuscleCytoskeleloncytoplasmic212372_at3,52E-06
PDGFD6,44Platelet-derived growth factor DSignalingSecreted219304_s_at7,71E-08
COLEC126,31Collectin subfamily member 12Host defensePlasma membrane221019_s_at7,51E-08
PXDN6,26Peroxidasin homologue (Drosophila)RedoxSecreted/ECM212013_at2.13E-08
HSPA1A6,25Heat shock 70 kDa protein 1AChaperonIntracellular200799_at2,30E-08
SLC2A106,23Solute currier family 2 (facilitated glucose transporter), member 10TransportPlasma membrane221024_s_at3,98E-07
NIDI6,18Nidogen 1AdhesionSecreted/ECM202007_at7,51E-08
TUSC36,10Tumor suppressor candidate 3N-GlycosylationER213423_x_at2,30E-08
RHBDL26,07Rhomboid, veinlet-like 2 (Drosophila)SignalingPlasma membrane219489_s_at7,67E-08
GABRA25,92γ-Aminobutyric acid (GABA) A receptor, α 2Ion transportPlasma membrane207014_at2,77E-06
CYTL15,84Cytokine-like 1SignalingSecreted219837_s_at1,53E-08
NPTX15,78Neuronal pentraxin ISynaptic transmissionIntracellular204684_at5,82E-08
EREG−8,27EpiregulinSignalingSecreted205767_at3,14E-08
GREM1−7,90Gremlin 1, cysteine knot superfamily, homologue (Xenopus laevis)SignalingSecreted218468_s_at7,68E-08
PRSS7−7,38Protease, serine, 7 (enterokinase)ProteolysisPlasma Membrane207638_at5,39E-08
FABP5−7,22Fatty acid binding protein 5 (psoriasis associated)TransportCytoplasmic202345_s_at1,57E-08
NETO2−6,91Neuropilin (NRP) and tolloid (TLL)-like 2Signaling?Plasma Membrane218888_s_at5,32E-08
NRIP3−6,73Nuclear receptor interacting protein 3UnknownUnknown219557_s_at5.82E-08
ETVl−6,62Ets variant gene 1TrancriptionNuclear221911_at7,68E-08
C3orf14−6,42Chromosome 3 open reading frame 14UnknownUnknown219288_at8,02E-08
SVIL−6,41SupervillinCytoskeletonPlasma Membrane202565_s_at373E-08
PLAGL1−5,86Pleiomorphic adenoma gene-like 1TrancriptionNuclear/Cytoplasm.209318_x_at1.11E-06
PKIA−5,67Protein kinase (CAMP-dependent, catalytic) inhibitor αSignalingNuclear/Cytoplasm.204612_at2,55E-08
MCTP1−5,65Multiple C2 domains, transmembrane 1UnknownPlasmaMembrane220122_at8.54E-07
MYO1B−5,64Myosin IBCytoskeletonCytoplasmic212364_at167E-07
HGF−5,55Hepatneyte growth factor (hepapoietin A; scatter factor)SignalingSecreted210997_at2,55E-08
ABCA1−5,50ATP-binding cassette, subfamily A (ABC1), member 1TransportPlasma Membrane203504_s_at5.94E-08
AHNAK2−5,47AHNAK nucleoprotein 2TransportSecreted212992_at8,35E-08
PLTP−5,45Phospholipid transfer proteinScaffoldingNuclear/Cytoplasm.202075_s_at8,29E-08
PRRX1−5,38Paired related homeobox 1TrancriptionNuclear205991_s_at1,13E-07
HS3ST3A1−5,35Heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1ECM modifierPlasma Membrane219985_at6,19E-08
UGT8−5,34UDP glycosyltransferase 8Sphingolipids biosynth.ER208358_s_at3,43E-07
  • *(log2) − mean fold differences.