Table 1.

Antiproliferative potencies of cannabinoids during a 3-d treatment of MDA-MB231 and MDA-MB436 breast cancer cells

CompoundMDA-MB231MDA-MB436
Embedded ImageΔ9-THC1.2 (1.0–1.4)2.5 (1.8–3.4)
Embedded ImageCBN1.2 (0.9–1.5)2.6 (1.8–3.7)
Embedded ImageWIN55,212-21.7 (1.5–2.2)2.4 (1.6–3.4)
Embedded ImageCP55,9402.5 (1.5–4.1)1.3 (0.7–1.6)
Embedded ImageCBD1.3 (1.0–1.9)1.6 (1.1–2.2)
Embedded ImageCBG2.3 (2.1–2.5)2.1 (1.5–3.0)
  • NOTE: Cells were treated with cannabinoid compounds for 3 d and the IC50 values for the antiproliferative effects of the compounds were calculated. Data are the means and corresponding 95% confidence limits of at least three experiments. IC50 values are reported in μmol/L.