Table 2.

Overexpression of ATF3 modulates the expression of genes related to invasion

GeneFold change mRNA expression
ATF3 overexpression*30 μmol/L sulindac sulfide
ATF35.8 ± 0.338.6 ± 0.45
Maspin1.9 ± 0.120.56 ± 0.04
PAI-11.7 ± 0.083.41 ± 0.54
MTA-10.73 ± 0.010.91 ± 0.08
β-Catenin0.73 ± 0.020.79 ± 0.03
  • NOTE: mRNA expression was measured by real-time RT-PCR on Ct values adjusted for actin.

  • * Values are expressed as mean (±SE) fold change relative to vector-transfected vehicle-treated cells.

  • Values are expressed as mean (±SE) fold change relative to time-matched vehicle-treated cells.