Review:

Molecular Biology of Bone Metastasis

Lauren A. Kingsley, Pierrick G.J. Fournier, John M. Chirgwin, and Theresa A. Guise
Mol Cancer Ther 2007 6: 2609-2617 doi: 10.1158/1535-7163.MCT-07-0234 [Abstract] [Full Text] [PDF]  

Research Articles: Therapeutics, Targets, and Development:

Formyl peptide receptor-like 1–mediated endogenous TRAIL gene expression with tumoricidal activity

Chentao Lin, Wei Wei, Jinchun Zhang, Shilian Liu, Yanxin Liu, and Dexian Zheng
Mol Cancer Ther 2007 6: 2618-2625 doi: 10.1158/1535-7163.MCT-07-0286 [Abstract] [Full Text] [PDF]  

The relevance of estrogen receptor-ß expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment

Mark Stettner, Silke Kaulfuß, Peter Burfeind, Stefan Schweyer, Arne Strauss, Rolf-Hermann Ringert, and Paul Thelen
Mol Cancer Ther 2007 6: 2626-2633Published Online First October 3, 2007. doi: 10.1158/1535-7163.MCT-07-0197 [Abstract] [Full Text] [PDF]  

Combined IFN- and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells

Cihan Cetinkaya, Anne Hultquist, Yingtao Su, Siqin Wu, Fuad Bahram, Sven Påhlman, Irina Guzhova, and Lars-Gunnar Larsson
Mol Cancer Ther 2007 6: 2634-2641 doi: 10.1158/1535-7163.MCT-06-0492 [Abstract] [Full Text] [PDF]  

Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non–small cell lung cancers

Jacqueline F. Doody, Ying Wang, Sheetal N. Patel, Christopher Joynes, Sui Ping Lee, Jason Gerlak, Robin L. Rolser, Yanxia Li, Philipp Steiner, Rajiv Bassi, Dan J. Hicklin, and Yaron R. Hadari
Mol Cancer Ther 2007 6: 2642-2651Published Online First October 3, 2007. doi: 10.1158/1535-7163.MCT-06-0506 [Abstract] [Full Text] [PDF]  

Expression of epidermal growth factor (EGF)/transforming growth factor- by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice

Wenjuan Wu, Michael S. O'Reilly, Robert R. Langley, Rachel Z. Tsan, Cheryl H. Baker, Neby Bekele, Xi Ming Tang, Amir Onn, Isaiah J. Fidler, and Roy S. Herbst
Mol Cancer Ther 2007 6: 2652-2663Published Online First October 3, 2007. doi: 10.1158/1535-7163.MCT-06-0759 [Abstract] [Full Text] [PDF]  

Response to trastuzumab, erlotinib, and bevacizumab, alone and in combination, is correlated with the level of human epidermal growth factor receptor-2 expression in human breast cancer cell lines

David R. Emlet, Kathryn A. Brown, Deborah L. Kociban, Agnese A. Pollice, Charles A. Smith, Ben Brian L. Ong, and Stanley E. Shackney
Mol Cancer Ther 2007 6: 2664-2674 doi: 10.1158/1535-7163.MCT-07-0079 [Abstract] [Full Text] [PDF]  

IB05204, a dichloropyridodithienotriazine, inhibits angiogenesis in vitro and in vivo

Beatriz Martínez-Poveda, Ramón Muñoz-Chápuli, Salvador Rodríguez-Nieto, José M. Quintela, Antonio Fernández, Miguel-Ángel Medina, and Ana R. Quesada
Mol Cancer Ther 2007 6: 2675-2685 doi: 10.1158/1535-7163.MCT-07-0136 [Abstract] [Full Text] [PDF]  

Honokiol causes G₀-G₁ phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity

Eun-Ryeong Hahm and Shivendra V. Singh
Mol Cancer Ther 2007 6: 2686-2695 doi: 10.1158/1535-7163.MCT-07-0217 [Abstract] [Full Text] [PDF]  

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells

Srirupa Roy, Manjinder Kaur, Chapla Agarwal, Marianne Tecklenburg, Robert A. Sclafani, and Rajesh Agarwal
Mol Cancer Ther 2007 6: 2696-2707 doi: 10.1158/1535-7163.MCT-07-0104 [Abstract] [Full Text] [PDF]  

DNA sequence–selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145

Konstantinos Kiakos, Atsushi Sato, Tetsuji Asao, Peter J. McHugh, Moses Lee, and John A. Hartley
Mol Cancer Ther 2007 6: 2708-2718 doi: 10.1158/1535-7163.MCT-07-0294 [Abstract] [Full Text] [PDF]  

Thioredoxin-like domains required for glucose regulatory protein 58–mediated reductive activation of mitomycin C leading to DNA cross-linking

Anbu Karani Adikesavan and Anil K. Jaiswal
Mol Cancer Ther 2007 6: 2719-2727 doi: 10.1158/1535-7163.MCT-07-0160 [Abstract] [Full Text] [PDF]  

Treatment of metastatic renal cancer with capsid-modified oncolytic adenoviruses

Kilian Guse, Tuuli Ranki, Martti Ala-Opas, Petri Bono, Merja Särkioja, Maria Rajecki, Anna Kanerva, Tanja Hakkarainen, and Akseli Hemminki
Mol Cancer Ther 2007 6: 2728-2736 doi: 10.1158/1535-7163.MCT-07-0176 [Abstract] [Full Text] [PDF]  

Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells

Audrey Roth, Daryl C. Drummond, Fraser Conrad, Mark E. Hayes, Dmitri B. Kirpotin, Christopher C. Benz, James D. Marks, and Bin Liu
Mol Cancer Ther 2007 6: 2737-2746 doi: 10.1158/1535-7163.MCT-07-0140 [Abstract] [Full Text] [PDF]  

Treatment of colon cancer cells using the cytosine deaminase/5-fluorocytosine suicide system induces apoptosis, modulation of the proteome, and Hsp90ß phosphorylation

Luc Negroni, Michel Samson, Jean-Marie Guigonis, Bernard Rossi, Valérie Pierrefite-Carle, and Christian Baudoin
Mol Cancer Ther 2007 6: 2747-2756 doi: 10.1158/1535-7163.MCT-07-0040 [Abstract] [Full Text] [PDF]  

Inactivation of NF-B by 3,3'-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells

KM Wahidur Rahman, Shadan Ali, Amro Aboukameel, Sanila H. Sarkar, Zhiwei Wang, Philip A. Philip, Wael A. Sakr, and Avraham Raz
Mol Cancer Ther 2007 6: 2757-2765Published Online First October 3, 2007. doi: 10.1158/1535-7163.MCT-07-0336 [Abstract] [Full Text] [PDF]  

Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim

Keith S. Abayasiriwardana, Dario Barbone, Ki-Up Kim, Claire Vivo, Kevin K. Lee, Tobias B. Dansen, Abigail E. Hunt, Gerard I. Evan, and V. Courtney Broaddus
Mol Cancer Ther 2007 6: 2766-2776 doi: 10.1158/1535-7163.MCT-07-0278 [Abstract] [Full Text] [PDF]  

Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism

Caroline G. Roberts, Ebru Gurisik, Trevor J. Biden, Robert L. Sutherland, and Alison J. Butt
Mol Cancer Ther 2007 6: 2777-2785Published Online First October 3, 2007. doi: 10.1158/1535-7163.MCT-07-0374 [Abstract] [Full Text] [PDF]  

Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization–independent activation of the nuclear factor-B/IB kinase signal pathway

Seung Ho Lee, Seung Mo Son, Dong Ju Son, Sun Mi Kim, Tack Joong Kim, Sukgil Song, Dong Cheul Moon, Hyo Won Lee, Jae Chun Ryu, Do-Young Yoon, and Jin Tae Hong
Mol Cancer Ther 2007 6: 2786-2797 doi: 10.1158/1535-7163.MCT-07-0002 [Abstract] [Full Text] [PDF]  

Amino acid substitutions at proline 220 of ß-tubulin confer resistance to paclitaxel and colcemid

Shanghua Yin, Fernando Cabral, and Sudha Veeraraghavan
Mol Cancer Ther 2007 6: 2798-2806 doi: 10.1158/1535-7163.MCT-06-0791 [Abstract] [Full Text] [PDF]  

O⁶-Methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor–induced resistance against temozolomide in human melanoma cells

Dennis Fontijn, Auke D. Adema, Kishor K. Bhakat, Herbert M. Pinedo, Godefridus J. Peters, and Epie Boven
Mol Cancer Ther 2007 6: 2807-2815 doi: 10.1158/1535-7163.MCT-07-0044 [Abstract] [Full Text] [PDF]  

Correction:

Mol Cancer Ther 2007 6: 2816 doi: 10.1158/1535-7163.MCT-06-10-COR [Full Text] [PDF]  

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