Immunofluorescence staining of NIH3T3 cells treated with DMSO (control, left column) or diallyl disulfide (56 μmol/L, right column), a garlic-derived organosulfur compound. In interphase cells, treatment with diallyl disulfide induces micronuclei formation (right column, upper panel) and microtubule stabilization (right column, middle panel). In mitotic cells, treatment with diallyl disulfide interferes with spindle-MT functions and induces the formation of lagging chromosomes (right column, lower panel). Chromosomal DNA is stained blue; microtubules, green; and stabilized microtubules, red. For details, see Xiao et al. in this issue.