Articles:

Identification of genes and molecular pathways involved in the progression of premalignant oral epithelia

Abhijit G. Banerjee, Indraneel Bhattacharyya, and Jamboor K. Vishwanatha
Mol Cancer Ther 2005 4: 865-875 doi: 10.1158/1535-7163.MCT-05-0033 [Abstract] [Full Text] [PDF] Supplementary Data  

Selective and irreversible cell cycle inhibition by diphenyleneiodonium

Robin M. Scaife
Mol Cancer Ther 2005 4: 876-884 doi: 10.1158/1535-7163.MCT-05-0009 [Abstract] [Full Text] [PDF]  

In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells

Hans Minderman, Jeffrey M. Conroy, Kieran L. O'Loughlin, Devin McQuaid, Paul Quinn, Song Li, Lakshmi Pendyala, Norma J. Nowak, and Maria R. Baer
Mol Cancer Ther 2005 4: 885-900 doi: 10.1158/1535-7163.MCT-04-0048 [Abstract] [Full Text] [PDF]  

Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH₂-kinase pathway

Yin Li, Yuehua Mao, Paul W. Brandt-Rauf, Ann C. Williams, and Robert L. Fine
Mol Cancer Ther 2005 4: 901-909 doi: 10.1158/1535-7163.MCT-04-0206 [Abstract] [Full Text] [PDF]  

ZM336372, a Raf-1 activator, suppresses growth and neuroendocrine hormone levels in carcinoid tumor cells

Jamie J. Van Gompel, Muthusamy Kunnimalaiyaan, Kyle Holen, and Herbert Chen
Mol Cancer Ther 2005 4: 910-917 doi: 10.1158/1535-7163.MCT-04-0334 [Abstract] [Full Text] [PDF]  

Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells via inhibition of both rapamycin-sensitive and -insensitive pathways

Chia-Ling Gau, Juran Kato-Stankiewicz, Chen Jiang, Susie Miyamoto, Lea Guo, and Fuyuhiko Tamanoi
Mol Cancer Ther 2005 4: 918-926 doi: 10.1158/1535-7163.MCT-04-0347 [Abstract] [Full Text] [PDF]  

In vitro cytotoxicity of carcinoma cells with ¹¹¹In-labeled antibodies to HER-2

Rosana B. Michel, Philip M. Andrews, Mary Ellen Castillo, and M. Jules Mattes
Mol Cancer Ther 2005 4: 927-937 doi: 10.1158/1535-7163.MCT-04-0340 [Abstract] [Full Text] [PDF]  

Plasma vascular endothelial growth factor and interleukin-8 as biomarkers of antitumor efficacy of a prototypical erbB family tyrosine kinase inhibitor

James G. Christensen, Patrick W. Vincent, Wayne D. Klohs, David W. Fry, Wilbur R. Leopold, and William L. Elliott
Mol Cancer Ther 2005 4: 938-947 doi: 10.1158/1535-7163.MCT-04-0208 [Abstract] [Full Text] [PDF]  

A phase I clinical trial of a ribozyme-based angiogenesis inhibitor targeting vascular endothelial growth factor receptor-1 for patients with refractory solid tumors

David E. Weng, Paul A. Masci, Susan F. Radka, T. Elise Jackson, Patricia A. Weiss, Ram Ganapathi, Paul J. Elson, William B. Capra, Vann P. Parker, Jennifer A. Lockridge, J. Wayne Cowens, Nassim Usman, and Ernest C. Borden
Mol Cancer Ther 2005 4: 948-955 doi: 10.1158/1535-7163.MCT-04-0210 [Abstract] [Full Text] [PDF]  

Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein

Hyun-Mi Cho, Joseph D. Rosenblatt, Young-Sook Kang, M. Luisa Iruela-Arispe, Sherie L. Morrison, Manuel L. Penichet, Young-Guen Kwon, Tae-Woong Kim, Keith A. Webster, Hovav Nechustan, and Seung-Uon Shin
Mol Cancer Ther 2005 4: 956-967 doi: 10.1158/1535-7163.MCT-04-0321 [Abstract] [Full Text] [PDF]  

Sapphyrins induce apoptosis in hematopoietic tumor–derived cell lines and show in vivo antitumor activity

Louie Naumovski, Jason Ramos, Mint Sirisawad, Jun Chen, Patti Thiemann, Philip Lecane, Darren Magda, Zhong Wang, Cecilia Cortez, Garry Boswell, Dong Gyu Cho, Jonathan Sessler, and Richard Miller
Mol Cancer Ther 2005 4: 968-976 doi: 10.1158/1535-7163.MCT-04-0339 [Abstract] [Full Text] [PDF]  

Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

Yan Luo, Alexander R. Shoemaker, Xuesong Liu, Keith W. Woods, Sheela A. Thomas, Ron de Jong, Edward K. Han, Tongmei Li, Vincent S. Stoll, Jessica A. Powlas, Anatol Oleksijew, Michael J. Mitten, Yan Shi, Ran Guan, Thomas P. McGonigal, Vered Klinghofer, Eric F. Johnson, Joel D. Leverson, Jennifer J. Bouska, Mulugeta Mamo, Richard A. Smith, Emily E. Gramling-Evans, Bradley A. Zinker, Amanda K. Mika, Phong T. Nguyen, Tilman Oltersdorf, Saul H. Rosenberg, Qun Li, and Vincent L. Giranda
Mol Cancer Ther 2005 4: 977-986 doi: 10.1158/1535-7163.MCT-05-0005 [Abstract] [Full Text] [PDF]  

A highly epothilone B–resistant A549 cell line with mutations in tubulin that confer drug dependence

Chia-Ping Huang Yang, Pascal Verdier-Pinard, Fang Wang, Eva Lippaine-Horvath, Lifeng He, Dansu Li, Gerhard Höfle, Iwao Ojima, George A. Orr, and Susan Band Horwitz
Mol Cancer Ther 2005 4: 987-995 doi: 10.1158/1535-7163.MCT-05-0024 [Abstract] [Full Text] [PDF]  

Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity

Shu-Jie He, Graham Stevens, Antony W. Braithwaite, and Michael R. Eccles
Mol Cancer Ther 2005 4: 996-1003 doi: 10.1158/1535-7163.MCT-04-0252 [Abstract] [Full Text] [PDF]  

The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer

Christopher J. Sweeney, Sanjana Mehrotra, Miral R. Sadaria, Suresh Kumar, Nicholas H. Shortle, Yaritzabel Roman, Carol Sheridan, Robert A. Campbell, Daryl J. Murry, Sunil Badve, and Harikrishna Nakshatri
Mol Cancer Ther 2005 4: 1004-1012 doi: 10.1158/1535-7163.MCT-05-0030 [Abstract] [Full Text] [PDF]  

Conditionally replicative adenovirus expressing degradation-resistant p53 for enhanced oncolysis of human cancer cells overexpressing murine double minute 2

Victor W. van Beusechem, Petra B. van den Doel, and Winald R. Gerritsen
Mol Cancer Ther 2005 4: 1013-1018 doi: 10.1158/1535-7163.MCT-05-0010 [Abstract] [Full Text] [PDF]  

p53 -Helix mimetics antagonize p53/MDM2 interaction and activate p53

Lihong Chen, Hang Yin, Bilal Farooqi, Said Sebti, Andrew D. Hamilton, and Jiandong Chen
Mol Cancer Ther 2005 4: 1019-1025 doi: 10.1158/1535-7163.MCT-04-0342 [Abstract] [Full Text] [PDF]  

Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine–resistant cancer cells

Kurtis E. Bachman, Jason Sager, Ian Cheong, Marco Catto, Alberto Bardelli, Ben Ho Park, Bert Vogelstein, Angelo Carotti, Kenneth W. Kinzler, and Christoph Lengauer
Mol Cancer Ther 2005 4: 1026-1030 doi: 10.1158/1535-7163.MCT-05-0038 [Abstract] [Full Text] [PDF]  

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