Articles:

Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis in vitro and in vivo in prostate cancer cell lines

Beverly E. Barton, Thomas F. Murphy, Ping Shu, Hosea F. Huang, Marcus Meyenhofen, and Arnold Barton
Mol Cancer Ther 2004 3: 1183-1191 [Abstract] [Full Text] [PDF]  

Targeting heterogeneous nuclear ribonucleoparticule A1 and A2 proteins by RNA interference promotes cell death in transformed but not in normal mouse cell lines

Caroline Patry, Bruno Lemieux, Raymund J. Wellinger, and Benoit Chabot
Mol Cancer Ther 2004 3: 1193-1199 [Abstract] [Full Text] [PDF]  

A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells

Christopher M. Incles, Christoph M. Schultes, Helena Kempski, Heike Koehler, Lloyd R. Kelland, and Stephen Neidle
Mol Cancer Ther 2004 3: 1201-1206 [Abstract] [Full Text] [PDF]  

Topoisomerase-II expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel

Virginie Durbecq, Marianne Paesmans, Fatima Cardoso, Christine Desmedt, Angelo Di Leo, Stephen Chan, Kay Friedrichs, Tamas Pinter, Simon Van Belle, Elizabeth Murray, István Bodrogi, Euan Walpole, Bernard Lesperance, Stefan Korec, John Crown, Peter Simmonds, Thimothy J. Perren, Jean-Yves Leroy, Ghizlane Rouas, Christos Sotiriou, Martine Piccart, and Denis Larsimont
Mol Cancer Ther 2004 3: 1207-1214 [Abstract] [Full Text] [PDF]  

Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O⁶-alkylguanine-DNA alkyltransferase

Vincent A. Barvaux, Paul Lorigan, Malcolm Ranson, Amanda M. Gillum, R. Stanley McElhinney, T. Brian H. McMurry, and Geoffrey P. Margison
Mol Cancer Ther 2004 3: 1215-1220 [Abstract] [Full Text] [PDF]  

Inhibition of Chk1 by the G₂ DNA damage checkpoint inhibitor isogranulatimide

Xiuxian Jiang, Baoguang Zhao, Robert Britton, Lynette Y. Lim, Dan Leong, Jasbinder S. Sanghera, Bin-Bing S. Zhou, Edward Piers, Raymond J. Andersen, and Michel Roberge
Mol Cancer Ther 2004 3: 1221-1227 [Abstract] [Full Text] [PDF]  

G₂ cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium

Robin M. Scaife
Mol Cancer Ther 2004 3: 1229-1237 [Abstract] [Full Text] [PDF]  

The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice

Nhu-An Pham, James W. Jacobberger, Aaron D. Schimmer, Pinjiang Cao, Marcella Gronda, and David W. Hedley
Mol Cancer Ther 2004 3: 1239-1248 [Abstract] [Full Text] [PDF]  

Peroxisome proliferator-activated receptor and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

Marina Konopleva, Elena Elstner, Teresa J. McQueen, Twee Tsao, Andrey Sudarikov, Wei Hu, Wendy D. Schober, Rui-Yu Wang, David Chism, Steven M. Kornblau, Anas Younes, Steven J. Collins, H. Phillip Koeffler, and Michael Andreeff
Mol Cancer Ther 2004 3: 1249-1262 [Abstract] [Full Text] [PDF]  

Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor

Qun Xu, Michelle Farah, Jack M. Webster, and Richard J.H. Wojcikiewicz
Mol Cancer Ther 2004 3: 1263-1269 [Abstract] [Full Text] [PDF]  

Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model

Gilda G. Hillman, Yu Wang, Omer Kucuk, Mingxin Che, Daniel R. Doerge, Mark Yudelev, Michael C. Joiner, Brian Marples, Jeffrey D. Forman, and Fazlul H. Sarkar
Mol Cancer Ther 2004 3: 1271-1279 [Abstract] [Full Text] [PDF]  

BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors

Hidesuke Fukazawa, Kohji Noguchi, Atsuko Masumi, Yuko Murakami, and Yoshimasa Uehara
Mol Cancer Ther 2004 3: 1281-1288 [Abstract] [Full Text] [PDF]  

Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists

Jesus V. Soriano, Ningfei Liu, Yang Gao, Zhu-Jun Yao, Toshio Ishibashi, Charles Underhill, Terrence R. Burke, Jr., and Donald P. Bottaro
Mol Cancer Ther 2004 3: 1289-1299 [Abstract] [Full Text] [PDF]  

Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway

Eddy Pasquier, Manon Carré, Bertrand Pourroy, Laurence Camoin, Ouafa Rebaï, Claudette Briand, and Diane Braguer
Mol Cancer Ther 2004 3: 1301-1310 [Abstract] [Full Text] [PDF]  

Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome

Qing Chen, Sheng Tong, Mark W. Dewhirst, and Fan Yuan
Mol Cancer Ther 2004 3: 1311-1317 [Abstract] [Full Text] [PDF]  

Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in -tubulin

Frank Loganzo, Malathi Hari, Tami Annable, Xingzhi Tan, Daniel B. Morilla, Sylvia Musto, Arie Zask, Joshua Kaplan, Albert A. Minnick, Jr., Michael K. May, Semiramis Ayral-Kaloustian, Marianne S. Poruchynsky, Tito Fojo, and Lee M. Greenberger
Mol Cancer Ther 2004 3: 1319-1327 [Abstract] [Full Text] [PDF]  

Novel peptide ligands for integrin ₄ß₁ overexpressed in cancer cells

Masahito Mikawa, Henry Wang, Linlang Guo, Ruiwu Liu, Jan Marik, Yoshikazu Takada, Kit Lam, and Derick Lau
Mol Cancer Ther 2004 3: 1329-1334 [Abstract] [Full Text] [PDF]  

Minireview:

Targeting ErbB receptor signaling: A pan-ErbB approach to cancer

Carolyn D. Britten
Mol Cancer Ther 2004 3: 1335-1342 [Abstract] [Full Text] [PDF]  

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