Article Figures & Data
Additional Files
Supplementary Data
- Supplementary Material - Chemical Synthesis of APTO-253
- Figure S1 - Influx and efflux of APTO-253 and Fe(253)3.
- Figure S2 - The accumulation of phospho-ATM, γ-H2AFX and cleaved PARP in Raji compared to that in Raji/253R cells exposed to APTO-253 for 24 h.
- Figure S3 - Role of ABCG2 in resistance to Fe(253)3.
- Table S1 - Rate of efflux of APTO-253 and Fe(253)3 from Raji and Raji/253R cells over first 2 hours (log fmole/10^7 cells/h)
- Table S2 - Rank order of genes up-regulated in Raji/253R cells.
- Table S3 - ABC transporter family member genes up-regulated in Raji/253R cells