Article Figures & Data
- Supplementary Materials and Methods and Supplementary Figures S1-S4 - 1. Supplementary Materials and Methods 2. Figure S1. DNA sequence alignment of Fas or FasL Crispr knockout gene with their parent gene. 3. Figure S2. Cell viability, caspase-3 cleavage and the phosphorylation of ERK1/2, p38, I-ÎºB and NF-ÎºB in Cal-27 cells with Fas neutralization. 4. Figure S3. FasL Crispr knockout enhances the cytotoxic effectiveness of hcc49scFv-FasL on Cal-27 cells. 5. Figure S4. hcc49scFV-FasL fusion protein cannot be cleaved by ADAM10 and MMP-7.