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Molecular Cancer Therapeutics
Molecular Cancer Therapeutics

Advanced Search

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
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    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
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    • Submit
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Index by author

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A

  1. Ahmed, Saira

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  2. Airhart, Susan

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  3. Albert, Daniel H.

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  4. Altwerger, Gary

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  5. Alvarenga, Julio

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  6. Arioli, Ivano

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  7. Atoyan, Ruzanna

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  8. Azodi, Masoud

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  9. Azuma, Koichi

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

B

  1. Baracos, Vickie E.

    1. Commentary
      Mitogen-Activated Protein Kinases Inhibitors: Potential Therapeutic Agents for Cancer Cachexia
      Vickie E. Baracos
      Mol Cancer Ther February 1 2017 16 (2) 263-264; DOI:10.1158/1535-7163.MCT-16-0753

  2. Barajas, Juan M.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  3. Batteux, Frédéric

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  4. Bekaii-Saab, Tanios

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  5. Bellone, Matteo

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  6. Bellone, Stefania

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  7. Benoit, Evelyne

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  8. Black, Jonathan D.

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  9. Bloomston, Mark

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  10. Bonazzoli, Elena

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  11. Bongiovanni, Lucia

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  12. Borek, Mylissa A.

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  13. Bortolomai, Ileana

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  14. Botti, Laura

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  15. Bui, Nam

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

C

  1. Caligiuri, Michael A.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  2. Cancila, Valeria

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  3. Cerles, Olivier

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  4. Chamie, Karim

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  5. Che, Zheng

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  6. Cheng, Guo

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  7. Chiba, Masato

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  8. Chiodoni, Claudia

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  9. Chouzenoux, Sandrine

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  10. Choyke, Peter L.

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  11. Chéreau, Christiane

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  12. Cimino, George D.

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  13. Clark, Mitchell

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  14. Cocco, Emiliano

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  15. Colombo, Mario P.

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  16. Coriat, Romain

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  17. Cui, Jiajia

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

D

  1. Da Costa, Elodie M.

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  2. Daar, Dagane

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  3. Dairiki, Ryo

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  4. Dellarocca, Steven

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  5. Deng, Yang

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  6. Drakaki, Alexandra

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

E

  1. Elnaggar, Omar

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

F

  1. Farren, Matthew R.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  2. Farris, Alton B.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  3. Fattaey, Ali

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  4. Festinese, Fabrizio

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  5. Frankel, Wendy L.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

G

  1. Gamo, Kanae

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  2. Gharibyan, Vazganush

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  3. Ghoshal, Kalpana

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  4. Guillaumot, Marie-Anne

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  5. Guttridge, Denis C.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

H

  1. Haack, Kurt

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  2. Han, Jianfeng

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  3. Hara, Ryujiro

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  4. He, Shun

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  5. Henderson, Paul T.

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  6. Hessler, Paul

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  7. Hikichi, Yukiko

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  8. Hoa, Tieu

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  9. Householder, Deborah

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  10. Hsu, Shu-Hao

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  11. Huang, Xiaoli

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  12. Husain, Hatim

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

I

  1. Imamura, Shinichi

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  2. Ishikawa, Yoshinori

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  3. Issa, Jean-Pierre J.

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  4. Iwatani, Misa

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

J

  1. Jachetti, Elena

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  2. Jacob, Samson T.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  3. Jie, Li

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  4. Jin, Lu

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  5. Jin-Lu, Huang

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

K

  1. Kamada, Yusuke

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  2. Kati, Warren M.

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  3. Kavian, Niloufar

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  4. Kim, Young Hak

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  5. Kobayashi, Hisataka

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  6. Kobayashi, Yoshihisa

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  7. Kurzrock, Razelle

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

L

  1. Lee, Justin T.

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  2. Lesinski, Gregory B.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  3. Li-Li, Wan

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  4. Lin, Ken

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  5. Lin, Tzu-yin

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  6. Lin, Xiaoyu

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  7. Litkouhi, Babak

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  8. Lopez, Salvatore

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  9. Loussier, Thomas

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

M

  1. Ma, Anna W.

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  2. Mace, Thomas A.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  3. Malfatti, Michael

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  4. Malouf, Gabriel G.

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  5. Marcellin, Louis

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  6. Maskarinec, Jennifer M.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  7. Matsumoto, Satoru

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  8. McDaniel, Keith F.

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  9. Menderes, Gulden

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  10. Mitsudomi, Tetsuya

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  11. Miyashita, Hitoshi

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  12. Morimoto, Megumi

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  13. Morin, Florence

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  14. Murtuza, Ayesha

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

N

  1. Nagai, Hiroki

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  2. Nagaya, Tadanobu

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  3. Nakamura, Kazuhide

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  4. Nakamura, Yuko

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  5. Nakayama, Akiko

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  6. Nakayama, Kazuhide

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  7. Nicco, Carole

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  8. Nishio, Kazuto

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  9. Nomura, Toshiyuki

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

O

  1. Ogata, Fusa

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  2. Ognibene, Ted

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  3. Ohler, Zoe Weaver

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  4. Okuyama, Shuhei

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

P

  1. Pan, Chong-xian

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  2. Parenza, Mariella

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  3. Patterson, Troy

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  4. Peng-Guo, Chen

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  5. Predolini, Federica

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

Q

  1. Quan-Jun, Yang

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

R

  1. Rajasekera, Priyani

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  2. Ratner, Elena

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  3. Raynal, Noël J.-M.

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  4. Rigoni, Alice

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  5. Roberts-Rapp, Lisa A.

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  6. Run, Gan

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

S

  1. Saidu, Nathaniel E.B.

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  2. Saltzman, W. Mark

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  3. Samson, Maria Elena S.

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  4. Santin, Alessandro D.

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  5. Santulli, Pietro

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  6. Sato, Katsuaki

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  7. Sato, Kazuhide

    1. Models and Technologies
      Near Infrared Photoimmunotherapy in a Transgenic Mouse Model of Spontaneous Epidermal Growth Factor Receptor (EGFR)-expressing Lung Cancer
      Yuko Nakamura, Zoe Weaver Ohler, Deborah Householder, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Dagane Daar, Tieu Hoa, Peter L. Choyke and Hisataka Kobayashi
      Mol Cancer Ther February 1 2017 16 (2) 408-414; DOI:10.1158/1535-7163.MCT-16-0663

  8. Sato, Takahiro

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  9. Schwab, Carlton L.

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  10. Schwartz, Peter E.

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  11. Scur, Michael

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

  12. Sesumi, Yuichi

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  13. Shapiro, Erik M.

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  14. Shen, Yu

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

  15. Shimoji, Masaki

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  16. Silasi, Dan-Arin

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  17. Snyder, Linda A.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  18. Sun, Kaiming

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

T

  1. Takagi, Shinji

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  2. Takemoto, Toshiki

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  3. Talbert, Erin E.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  4. Tardanico, Regina

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  5. Teng, Kun-Yu

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  6. Tepper, Clifford G.

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  7. Timmers, Cynthia D.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  8. Togashi, Yosuke

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  9. Tomita, Daisuke

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  10. Tomita, Naoki

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  11. Tomizawa, Kenji

    1. Cancer Biology and Signal Transduction
      Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer
      Yoshihisa Kobayashi, Koichi Azuma, Hiroki Nagai, Young Hak Kim, Yosuke Togashi, Yuichi Sesumi, Masato Chiba, Masaki Shimoji, Katsuaki Sato, Kenji Tomizawa, Toshiki Takemoto, Kazuto Nishio and Tetsuya Mitsudomi
      Mol Cancer Ther February 1 2017 16 (2) 357-364; DOI:10.1158/1535-7163.MCT-16-0407

  12. Toyoshima, Kosei

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  13. Tripodo, Claudio

    1. Cancer Biology and Signal Transduction
      Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β
      Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti, Mariella Parenza, Valeria Cancila, Claudia Chiodoni, Fabrizio Festinese, Matteo Bellone, Regina Tardanico, Claudio Tripodo and Mario P. Colombo
      Mol Cancer Ther February 1 2017 16 (2) 365-375; DOI:10.1158/1535-7163.MCT-16-0466

  14. Tsuchida, Ken

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  15. Tuck, David P.

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  16. Turteltaub, Kenneth W.

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

U

  1. Uziel, Tamar

    1. Companion Diagnostics and Cancer Biomarkers
      HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues
      Xiaoyu Lin, Xiaoli Huang, Tamar Uziel, Paul Hessler, Daniel H. Albert, Lisa A. Roberts-Rapp, Keith F. McDaniel, Warren M. Kati and Yu Shen
      Mol Cancer Ther February 1 2017 16 (2) 388-396; DOI:10.1158/1535-7163.MCT-16-0475

V

  1. Viner, Jaye L.

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

W

  1. Wang, Jing

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

  2. Wang, Si-Si

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  3. Wani, Nissar A.

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  4. Weill, Bernard

    1. Small Molecule Therapeutics
      Niclosamide Inhibits Oxaliplatin Neurotoxicity while Improving Colorectal Cancer Therapeutic Response
      Olivier Cerles, Evelyne Benoit, Christiane Chéreau, Sandrine Chouzenoux, Florence Morin, Marie-Anne Guillaumot, Romain Coriat, Niloufar Kavian, Thomas Loussier, Pietro Santulli, Louis Marcellin, Nathaniel E.B. Saidu, Bernard Weill, Frédéric Batteux and Carole Nicco
      Mol Cancer Ther February 1 2017 16 (2) 300-311; DOI:10.1158/1535-7163.MCT-16-0326

  5. Woodward, Brian

    1. Review
      Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer
      Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward and Razelle Kurzrock
      Mol Cancer Ther February 1 2017 16 (2) 265-272; DOI:10.1158/1535-7163.MCT-16-0105

X

  1. Xu, Guang-Xin

    1. Small Molecule Therapeutics | AuthorChoice
      Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers
      Kaiming Sun, Ruzanna Atoyan, Mylissa A. Borek, Steven Dellarocca, Maria Elena S. Samson, Anna W. Ma, Guang-Xin Xu, Troy Patterson, David P. Tuck, Jaye L. Viner, Ali Fattaey and Jing Wang
      Mol Cancer Ther February 1 2017 16 (2) 285-299; DOI:10.1158/1535-7163.MCT-16-0390

Y

  1. Yabuki, Masato

    1. Small Molecule Therapeutics
      A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells
      Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki, Shinji Takagi, Kosei Toyoshima, Kazuhide Nakayama, Akiko Nakayama, Megumi Morimoto, Hitoshi Miyashita, Ryo Dairiki, Yukiko Hikichi, Naoki Tomita, Daisuke Tomita, Shinichi Imamura, Misa Iwatani, Yusuke Kamada, Satoru Matsumoto, Ryujiro Hara, Toshiyuki Nomura, Ken Tsuchida and Kazuhide Nakamura
      Mol Cancer Ther February 1 2017 16 (2) 273-284; DOI:10.1158/1535-7163.MCT-16-0471

  2. Yan, Huo

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  3. Yang, Fan

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  4. Yang, Hongyuan

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  5. Yang, Jennifer

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  6. Yong-Long, Han

    1. Cancer Biology and Signal Transduction | AuthorChoice
      Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation
      Yang Quan-Jun, Huo Yan, Han Yong-Long, Wan Li-Li, Li Jie, Huang Jin-Lu, Lu Jin, Chen Peng-Guo, Gan Run and Guo Cheng
      Mol Cancer Ther February 1 2017 16 (2) 334-343; DOI:10.1158/1535-7163.MCT-16-0324

  7. Young, Gregory S.

    1. Cancer Biology and Signal Transduction
      Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities
      Erin E. Talbert, Jennifer Yang, Thomas A. Mace, Matthew R. Farren, Alton B. Farris, Gregory S. Young, Omar Elnaggar, Zheng Che, Cynthia D. Timmers, Priyani Rajasekera, Jennifer M. Maskarinec, Mark Bloomston, Tanios Bekaii-Saab, Denis C. Guttridge and Gregory B. Lesinski
      Mol Cancer Ther February 1 2017 16 (2) 344-356; DOI:10.1158/1535-7163.MCT-16-0337

  8. Yu, Jianhua

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

Z

  1. Zammataro, Luca

    1. Large Molecule Therapeutics
      Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells
      Emiliano Cocco, Yang Deng, Erik M. Shapiro, Ileana Bortolomai, Salvatore Lopez, Ken Lin, Stefania Bellone, Jiajia Cui, Gulden Menderes, Jonathan D. Black, Carlton L. Schwab, Elena Bonazzoli, Fan Yang, Federica Predolini, Luca Zammataro, Gary Altwerger, Christopher de Haydu, Mitchell Clark, Julio Alvarenga, Elena Ratner, Masoud Azodi, Dan-Arin Silasi, Peter E. Schwartz, Babak Litkouhi, W. Mark Saltzman and Alessandro D. Santin
      Mol Cancer Ther February 1 2017 16 (2) 323-333; DOI:10.1158/1535-7163.MCT-16-0501

  2. Zhang, Hanghang

    1. Models and Technologies
      Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
      Noël J.-M. Raynal, Elodie M. Da Costa, Justin T. Lee, Vazganush Gharibyan, Saira Ahmed, Hanghang Zhang, Takahiro Sato, Gabriel G. Malouf and Jean-Pierre J. Issa
      Mol Cancer Ther February 1 2017 16 (2) 397-407; DOI:10.1158/1535-7163.MCT-16-0588

  3. Zhang, Hongyong

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

  4. Zhang, Xiaoli

    1. Large Molecule Therapeutics
      Blocking the CCL2–CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
      Kun-Yu Teng, Jianfeng Han, Xiaoli Zhang, Shu-Hao Hsu, Shun He, Nissar A. Wani, Juan M. Barajas, Linda A. Snyder, Wendy L. Frankel, Michael A. Caligiuri, Samson T. Jacob, Jianhua Yu and Kalpana Ghoshal
      Mol Cancer Ther February 1 2017 16 (2) 312-322; DOI:10.1158/1535-7163.MCT-16-0124

  5. Zimmermann, Maike

    1. Companion Diagnostics and Cancer Biomarkers
      Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice
      Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W. Turteltaub, George D. Cimino, Clifford G. Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-xian Pan and Paul T. Henderson
      Mol Cancer Ther February 1 2017 16 (2) 376-387; DOI:10.1158/1535-7163.MCT-16-0381

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Molecular Cancer Therapeutics: 16 (2)
February 2017
Volume 16, Issue 2
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by Author
  • Editorial Board (PDF)

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Copyright 2016 by the American Association for Cancer Research.

Molecular Cancer Therapeutics
eISSN: 1538-8514
ISSN: 1535-7163

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